What’s In Your DNA?
DNA carries loads of information about how your body operates. Tiny parts of your DNA called genes provide unique instructions for your body’s tissue and organ function, food processing, and more. These instructions vary from person-to-person and are determined by base-pair substitutions. The majority of substitutions make little or no detectable difference in body function. However, clinical research has revealed which of these base-pair substitutions have the greatest impact on health and fitness - those are the ones we test.
How Do We Get It?
When your cheek swab arrives at the state-of-the-art testing facility, it is put through a series of solutions to extract your DNA. Through a process known as polymerase chain reaction (PCR), we increase the amount of the specific DNA segments on the gene that we want to test. The process involves heating the solution with the DNA to the temperature at which the two sides of the DNA molecule separate. We then add specific primers which have been designed to stick to the single strands of DNA at the beginning MTL Genetic analyzer and at the end of the specific segment we want to analyze.
The temperature is then lowered so the two chains can recombine. We then add a DNA polymerase to the solution which attaches to the strands of DNA at the sites where the primer has attached. Then a solution containing an abundance of the four base pairs, G, C, A and T, is added to the vessel and the DNA polymerase starts building a complementary DNA chain to the targeted area on the DNA. Time is allowed for the reaction to complete.
The temperature is then raised again to separate these segments and the process is repeated. One cycle lasts about four minutes and is repeated 20 to 30 times, yielding billions of copies of the targeted DNA sequence, all from the few cells that were contained on the cheek swab. Now that there is a significant amount of DNA with the target sequence, it can be put into an analyzer to determine what substitutions might be present in the sequence.
What Can It Tell You?
Hundreds of genes and DNA base-pair substitutions have been studied in order to select those that have the greatest impact on your health and fitness. We test these base-pairs and provide you with information that indicates where your greatest strengths lie so you can focus your efforts in those areas as well as identifies where your greatest challenges lurk so you can most effectively target them. Understanding your genetic profile empowers you to design the training routine and eating habits ideal for your unique genetic make-up.